Seroprevalence of parvovirus B19 among pregnant women in Tripoli, Libya
Methodology: A total number of 150 participants were included in the study, consisting of women of child-bearing age ranging from 18 to 41 years, and divided into age groups as follows: ≤ 21 years, 22-27, 28-32, 33-37, and ≥ 38 years. Specific IgM and IgG antibodies were measured using a commercial ELISA kit.
Results: IgG was observed to be prevalent (61%) among the women of child-bearing age. The sero-prevalence of IgM was found to be 5% overall and there was no detectable IgM in the age group between 33 and 37.
Conclusion: The presence of IgG and absence of IgM indicate immunity to primary infection, but a significant percentage of child-bearing aged women are at risk of primary infection with parvovirus B19 which could adversely affect their pregnancy.