A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India

Belgode Narasimha Harish; Godfred Antony Menezes; Kengamuthu Sarangapani; Subhash Chandra Parija

doi:10.3855/jidc.229

A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India

Authors

Belgode Narasimha Harish Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry
Godfred Antony Menezes Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry
Kengamuthu Sarangapani Department of Microbiology, Government General Hospital, Pondicherry
Subhash Chandra Parija Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Pondicherry

DOI:

https://doi.org/10.3855/jidc.229

Keywords:

Enteric fever, Salmonella Typhi, drug resistance

Abstract

Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64μg/ml. Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxone.

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Published

2008-08-01

How to Cite

Harish BN, Menezes GA, Sarangapani K, Parija SC (2008) A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India. J Infect Dev Ctries 2:324–327. doi: 10.3855/jidc.229

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Issue

Vol. 2 No. 04: August 2008

Section

Case Reports

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