IDR - Immune Diagnostics & Research

Case Reports

Sweet’s syndrome: a very rare association with pulmonary tuberculosis

Partha Sarathi Karmakar, Pasang Lahmu Sherpa, Achintya Narayan Ray, Bikram Kr. Saha, Tuhin Santra, Sanchita Saha, Indranil Chakrabarti

North Bengal Medical College and Hospital, Siliguri, West Bengal, India



Mycobacterium tuberculosis infection is a common infection in developing countries, including India. It can induce several cutaneous reactions such as erythema nodosum, and erythema induratum; however, association of tuberculosis with Sweet’s syndrome (also known as acute febrile neutrophilic dermatosis) is extremely rare. Here we present an interesting case of sputum-positive pulmonary tuberculosis with Sweet’s syndrome. A 55-year-old female who was receiving a regimen of four antitubercular drugs (isoniazid, rifampicin, pyrazinamide, ethambutol- HRZE) for six weeks for sputum-positive pulmonary tuberculosis developed new onset high-grade fever for 15 days along with multiple reddish brown plaques and nodules involving the face as well as all four limbs of the body. Histopathology of the skin lesion was suggestive of Sweet’s syndrome. The patient responded well to immunosuppressive steroid therapy.


acute febrile neutrophilic dermatosis; erythema nodosum; pyoderma gangrenosum

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