TY - JOUR AU - Poluga, Jasmina AU - Barac, Aleksandra AU - Katanic, Natasa AU - Rubino, Salvatore AU - Milosevic, Branko AU - Urosevic, Aleksandar AU - Mitrovic, Nikola AU - Kelic, Ivana AU - Micic, Jelena AU - Stevanovic, Goran PY - 2019/06/30 Y2 - 2024/03/28 TI - Tick-borne encephalitis in Serbia: A case series JF - The Journal of Infection in Developing Countries JA - J Infect Dev Ctries VL - 13 IS - 06 SE - Original Articles DO - 10.3855/jidc.11516 UR - https://www.jidc.org/index.php/journal/article/view/32058986 SP - 510-515 AB - <p>Introduction: In the Europe, the number of tick-borne encephalitis (TBE) has been increased in the last decade, and the number of endemic areas has been also increased and is still growing. In the present case series, we present clinical and socio-epidemiological data of patients with TBE hospitalized in the period of TBE virus epidemic in Serbia.</p><p>Methodology: A case series was conducted in Serbia in 2017. Patients with confirmed TBE were included in the study. Biochemical and serological analysis of blood and CSF, as well as radiological imaging (CT and MRI) were done.</p><p>Results: In total, 10 patients with TBE were included in the study. M:F ratio was 1.5:1, while average age was 45.1 years. Half of the patients had severe clinical picture. Endocranial CT scan and MRI did not reveal any abnormality, except in the patient with the most severe CNS infection (meningoencephalomyelitis). Mean value of sedimentation and CRP was slightly elevated (29.6 mm/1hours and 20.1 mg/L, respectively) in 80% of the patients, although elevation was almost negligible. The average number of leucocytes in the cerebrospinal fluid (CSF) was 171×10<sup>6</sup>/L, the mean value of the CSF protein was 1.1g/L. There were no fatal outcomes.</p><p>Conclusion: Since other CNS infections have similar clinical picture and CSF finding as TBE, serological analysis for TBE should be included in routine diagnostic practice.</p> ER -