IDR - Immune Diagnostics & Research

Regional Reviews

Global evidence directing regional preventive strategies in Southeast Asia for fighting TB/HIV

Myo Nyein Aung, Saiyud Moolphate, Damodar Paudel, Mangalasiri Jayathunge PH, Duangjai Duangrithi, Kinley Wangdi, Thin Nyein Nyein Aung, Thaworn Lorga, Kazue Higuchi

Department of Public Health, Juntendo University Graduate School of Medicine, Tokyo, Japan



Tuberculosis (TB) and human immunodeficiency virus (HIV) co-epidemics form a huge burden of disease in the Southeast Asia region. Five out of eleven nations in this region are high TB/HIV burden countries: Myanmar, Thailand, India, Indonesia and Nepal. The trends of TB incidence in these countries have been rising in recent years, in contrast to a falling global trend. Experts in the field of TB control and health service providers have been perplexed by the association of TB and HIV infections which causes a mosaic clinical presentation, a unique course with poor treatment outcomes including death. We conducted a review of contemporary evidence relating to TB/HIV control with the aims of assisting integrated health system responses in Southeast Asia and demystifying current evidence to facilitate translating it into practice.


TB/HIV; Southeast Asia; review; TB/HIV co-epidemics

Full Text: