Listeria monocytogenes brain abscess in a patient with multiple myeloma

Authors

  • Adil A Al-Khatti Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia
  • Jaffar A Al-Tawfiq Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia

DOI:

https://doi.org/10.3855/jidc.898

Keywords:

Invasive CNS disease, Meningitis, meningoencephalitis, Immunosuppression, Listeria

Abstract

Listeria monocytogenes is an uncommon cause of illness in the general population. Meningoencephalitis is the most common central nervous system (CNS) manifestation of listeriosis. However, brain abscess represents 1-10% of all CNS listeriosis. To our knowledge, L. monocytogenes brain abscess in multiple myeloma patients has not been previously reported. Thus we report a 58-year-old male patient with multiple myeloma who developed a brain abscess due to L. monocytogenes. Due to a history of penicillin allergy, he was treated with intravenous trimethoprim/sulfamoxazole (TMP-SMX) for a total of 12 weeks, and gentamicin for the first two weeks, followed by oral therapy of TMP-SMX for a total of nine months. He is alive six and a half years after the diagnosis of myeloma with occasional brief seizures despite being on two anticonvulsants.

Author Biographies

Adil A Al-Khatti, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia

1978: MB, BS; Excellent with first class honor, Faculty of Medicine, Riyadh University (now King Saud University.) Riyadh, Saudi Arabia.

1978-79:  Intern,  Riyadh University Affiliated Hospitals

1980-84: Medical Resident, Department of Medicine, University of British Columbia, Vancouver, BC, Canada

1984-88: Fellow and Senior Fellow in Hematology & Oncology, University of Washington, Seattle, WA, USA.

Diplomas:

1984: Specialist Certificate in Internal Medicine, The Royal College of Physicians and Surgeons of Canada.

1984: Diplomate of The American Board of, Internal Medicine (Internal Medicine).

1986: Diplomate of The American Board of Internal Medicine (Hematology).

1987:  Diplomate of The American Board of Internal Medicine (Medical Oncology)

Jaffar A Al-Tawfiq, Dhahran Health Center, Saudi Aramco Medical Services Organization, Saudi Aramco, Dhahran, Saudi Arabia

Dr. Jaffar A. Al-Tawfiq, MBBS, DTM&H, FACP, MISID is a consultant of internal medicine and infectious diseases at Saudi Aramco Medical Services Organization (SAMSO).  

He completed his internal medicine residency at Indiana University School of Medicine, Indiana (USA).  He subsequently completed Infectious Diseases Fellowship at the same university.

 

He is board certified in internal medicine and infectious diseases by the American Board of Internal Medicine.  During his Infectious Diseases fellowship, Dr. Al-Tawfiq did extensive work on the pathogenesis of Haemophilus ducreyi and the mechanism of the immune response to the various genes.  In 1998, he completed a diploma in Tropical Medicine and Hygiene (DTM&H) at London School of Tropical Medicine and Hygiene and was awarded a diploma in TM&H by the Royal College of Physician of London.  

 

During his academic career, Dr. Al-Tawfiq had multiple publications in different medical journal including: Journal of Infectious Diseases (JID), Clinical Infectious Diseases (CID), Annals of Pharmacotherapy, Southern Medical Journal, Infection and Immunity, Current Opinion in Infectious Disease, International Journal of Infectious Diseases (IJID) and Infection Control and Hospital Epidemiology.  

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Published

2010-07-21

How to Cite

1.
Al-Khatti AA, Al-Tawfiq JA (2010) Listeria monocytogenes brain abscess in a patient with multiple myeloma. J Infect Dev Ctries 4:849–851. doi: 10.3855/jidc.898

Issue

Vol. 4 No. 12: December 2010

Section

Case Reports

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