High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011

Authors

  • Shamsun Nahar Jahangirnagar University, Savar, Dhaka, Bangladesh
  • Mokibul Hassan Afrad Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh
  • Noorjahan Begum Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh
  • Feroz Al-Mamun Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh
  • Azadul Kabir Sarker Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh
  • Sumon Kumar Das Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh
  • Abu SG Faruque Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh
  • Mahmoud Reza Pourkarim Laboratory of Clinical and Epidemiological Virology, Rega Institute for Medical Research, University of Leuven, Leuven, Belgium
  • Mohammad Shabuddin Kabir Choudhuri Jahangirnagar University, Savar, Dhaka, Bangladesh
  • Tasnim Azim Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh
  • Mustafizur Rahman Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

DOI:

https://doi.org/10.3855/jidc.2944

Keywords:

Norovirus, diarrhea, Bangladesh

Abstract

Introduction: Norovirus is not usually investigated in diarrheal patients in Bangladesh which may account for the many cases where no pathogens are identified.

Methodology: Stool specimens collected from diarrheal patients from three hospitals in Bangladesh during 2011 were investigated for norovirus RNA using real-time RT-PCR assay with norovirus type specific primers and probes.

Results: Of the 257 stool specimens tested, 28.4 % were norovirus positive. GII (71.2%) was the predominant strain followed by GI (20.5%), GI+GII (6.8%) and GIV (1.4%). Half of the norovirus positive stools (n=37) were co-infected with other pathogens.

Conclusion: Continued surveillance of norovirus together with other viral and bacterial pathogens in hospitalized gastroenteritis patients as well as in the community will further elucidate the role and burden of different pathogens in diarrheal diseases.

Author Biographies

Shamsun Nahar, Jahangirnagar University, Savar, Dhaka, Bangladesh

Department of MicrobiologyAssistant professor

Mokibul Hassan Afrad, Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

Virology LaboratoryResearch officer

Noorjahan Begum, Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

Virology LaboratoryResearch officer

Feroz Al-Mamun, Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

Virology LaboratoryResearch officer

Azadul Kabir Sarker, Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

Virology LaboratoryResearch officer

Sumon Kumar Das, Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

Centre for Nutrition and Food SecurityResearch officer

Abu SG Faruque, Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

Centre for Nutrition and Food SecurityScientist

Mahmoud Reza Pourkarim, Laboratory of Clinical and Epidemiological Virology, Rega Institute for Medical Research, University of Leuven, Leuven, Belgium

Department of VirologyPhD student

Mohammad Shabuddin Kabir Choudhuri, Jahangirnagar University, Savar, Dhaka, Bangladesh

Department of PharmacyProfessor

Tasnim Azim, Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

International Centre for Diarrhoeal Disease Research, Bangladesh

Mustafizur Rahman, Virology Laboratory, icddr,b, Mohakhali, Dhaka-1212, Bangladesh

Virology LaboratoryAssociate scientist

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Published

2013-11-15

How to Cite

1.
Nahar S, Afrad MH, Begum N, Al-Mamun F, Sarker AK, Das SK, Faruque AS, Pourkarim MR, Choudhuri MSK, Azim T, Rahman M (2013) High prevalence of noroviruses among hospitalized diarrheal patients in Bangladesh, 2011. J Infect Dev Ctries 7:892–896. doi: 10.3855/jidc.2944

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Section

Brief Original Articles