Multidrug resistance in Pseudomonas aeruginosa isolated from nosocomial respiratory and urinary infections in Aleppo, Syria

  • Maysa Mahfoud Faculty of Pharmacy, University of Aleppo, Aleppo, Syria
  • Mona Al Najjar Centralized Clinical Microbiological Laboratory in Albasel and Ibn Rushd Hospitals, Aleppo, Syria
  • Abdul Rezzak Hamzeh Department of Biochemistry and Microbiology, Faculty of Pharmacy, University of Aleppo, Aleppo, Syria
Keywords: Pseudomonas aeruginosa, nosocomial infections, multidrug resistance, respiratory infections, urinary infections, Syria

Abstract

Introduction: Pseudomonas aeruginosa represents a serious clinical challenge due to its frequent involvement in nosocomial infections and its tendency towards multidrug resistance.

Methodology: This study uncovered antibiotic susceptibility patterns in 177 isolates from inpatients in three key hospitals in Aleppo, the largest city in Syria.

Results: Exceptionally low susceptibility to most routinely used antibiotics was uncovered; resistance to ciprofloxacin and gentamicin was 64.9% and 70.3%, respectively. Contrarily, susceptibility to colistin was the highest (89.1%).

Conclusions: Multidrug resistance was rife, found at a rate of 53.67% among studied P. aeruginosa isolates.

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Author Biography

Abdul Rezzak Hamzeh, Department of Biochemistry and Microbiology, Faculty of Pharmacy, University of Aleppo, Aleppo, Syria
Abdul Rezzak Hamzeh is a tenure-track assistant professor in molecular biology at the university of Aleppo. He received his PhD in molecular biology and genetics from the university of Manchester, UK. His publications include: “Prevalence of antibiotic resistance among Acinetobacter baumannii isolates from Aleppo, Syria” Am J Infect Control 2012 and “Catechol-O-methyltransferase Val 108/158 Met polymorphism and breast cancer Risk: A case–control study in Syria” Breast Cancer 2011.
Published
2015-02-19
How to Cite
1.
Mahfoud M, Al NajjarM, Hamzeh AR (2015) Multidrug resistance in Pseudomonas aeruginosa isolated from nosocomial respiratory and urinary infections in Aleppo, Syria. J Infect Dev Ctries 9:210-213. doi: 10.3855/jidc.5643
Section
Brief Original Articles