The emergence of Dengue Fever in Sheikhupura, Pakistan: its seroprevalence and risk factors assessment during 2014-2017

Muhammad Uzair Mukhtar; Maria Mukhtar; Naveed Iqbal; Zeeshan Nawaz; Adil Bhatti; Fatima Haq; Ali Arslan; Muhammad Rashid

doi:10.3855/jidc.13976

The emergence of Dengue Fever in Sheikhupura, Pakistan: its seroprevalence and risk factors assessment during 2014-2017

Authors

Muhammad Uzair Mukhtar State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 1, Lanzhou, Gansu, China
Maria Mukhtar Department of Biology, Government Degree College for women Shahrukn e Alam, Multan, Pakistan
Naveed Iqbal State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Xujiaping 1, Lanzhou, Gansu, China
Zeeshan Nawaz Department of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan
Adil Bhatti Directorate of Malaria Control, Ministry of National Health Services, Regulations and Coordination, Islamabad, Pakistan
Fatima Haq Health Department, Government of Punjab, Pakistan
Ali Arslan Punjab Livestock and Dairy Development Department, Pakistan
Muhammad Rashid Department of Parasitology, Faculty of Veterinary and Animal Sciences, The Islamia University Bahawalpur, Pakistan

DOI:

https://doi.org/10.3855/jidc.13976

Keywords:

Dengue, Prevalence, IgM, IgG, Pakistan

Abstract

Introduction: District Sheikhupura encountered its first dengue outbreak in 2014 but lacked serological evidence and reports of risk factors associated with it. To assess this, a hospital-based study was conducted from January 2014 to December 2017.

Methodology: Blood from 333 participants was collected, the serum obtained was tested for IgG and IgM antibodies against DENV using a commercially available ELISA kit.

Results: The results showed that out of all (n= 333) samples tested, 120 were turned up positive for DENV, making an overall prevalence of 36%. Of the 120 confirmed cases, 55% (n = 66) were recorded in 2014, 10% (n = 12) in 2015, 27.5% (n = 33) in 2016, and 7.5% (n = 9) in 2017. It was found that 68.3% (n = 82) were male and 31.7% (n = 38) were female, with 61% (n = 74) patients aged between 11-30 years. The highest prevalence of infection, 94.2% (n = 113), was noted after the rainy season. During the study, the highest number of cases appeared in Ferozewala Tehsil. The factors age, gender, and season were found statistically significant with the prevalence of infection (p < 0.05).

Conclusions: The study is the first report on the detection of dengue in the Sheikhupura district. The survey anticipated its geographical expansion, determined associated risk factors, and suggests active disease surveillance in the area.

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Published

2021-09-30

How to Cite

Mukhtar MU, Mukhtar M, Iqbal N, Nawaz Z, Bhatti A, Haq F, Arslan A, Rashid M (2021) The emergence of Dengue Fever in Sheikhupura, Pakistan: its seroprevalence and risk factors assessment during 2014-2017. J Infect Dev Ctries 15:1351–1355. doi: 10.3855/jidc.13976

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Issue

Vol. 15 No. 09: September 2021

Section

Brief Original Articles

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