Three elderly asymptomatic SARS-CoV-2 infected patients in ICU

Feng Zhou; Ye Li; Xuan Gao; Ying Zhang

doi:10.3855/jidc.13405

Three elderly asymptomatic SARS-CoV-2 infected patients in ICU

Authors

Feng Zhou Department of Endocrinology, Puren Hospital of Wuhan University of Science and Technology, Wuhan, China
Ye Li Department of Cardiology, Puren Hospital of Wuhan University of Science and Technology, Wuhan, China
Xuan Gao Department of Endocrinology, Puren Hospital of Wuhan University of Science and Technology, Wuhan, China
Ying Zhang Department of Critical care Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China

DOI:

https://doi.org/10.3855/jidc.13405

Keywords:

asymptomatic, COVID-19, elder age, ICU, IgG

Abstract

Previous studies on asymptomatic COVID-19 carriers indicated that asymptomatic infections always occurred in people in community or patients in general wards, prone to be young and middle aged people. Limited data are available for asymptomatic infections in critically ill patients in intensive care unit or elderly people. Here we reported three elderly asymptomatic SARS-CoV-2 infected patients in intensive care unit. These three elderly patients had negative CT images and 14 consecutive negative RT-PCR test results, with dynamic changes in IgG-IgM antibody levels without any clinical symptoms, which might be related to their weakened immune responses due to elder age (over 85 years old) and the history of hypertension. Therefore, combining nucleic acid RT-PCR and the IgM-IgG antibody test can provide more accurate SARS-CoV-2 infection diagnosis, especially for elderly asymptomatic patients.

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Published

2022-02-28

How to Cite

Zhou F, Li Y, Gao X, Zhang Y (2022) Three elderly asymptomatic SARS-CoV-2 infected patients in ICU. J Infect Dev Ctries 16:265–267. doi: 10.3855/jidc.13405

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Issue

Vol. 16 No. 02: February 2022

Section

Coronavirus Pandemic

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