Pseudoresistance to permethrin in scabies

Stefano Veraldi; Rossana Schianchi; Martina Silvio; Italo Francesco Aromolo

doi:10.3855/jidc.17750

Pseudoresistance to permethrin in scabies

Authors

Stefano Veraldi Department of Pathophysiology and Transplantation, Università degli Studi, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy https://orcid.org/0000-0002-0985-3590
Rossana Schianchi European Institute of Dermatology, Milan, Italy
Martina Silvio Department of Pathophysiology and Transplantation, Università degli Studi, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy https://orcid.org/0000-0002-4402-5213
Italo Francesco Aromolo Department of Pathophysiology and Transplantation, Università degli Studi, Foundation IRCCS, Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

DOI:

https://doi.org/10.3855/jidc.17750

Keywords:

Sarcoptes scabiei var. hominis, scabies, permethrin, pseudoresistance, resistance

Abstract

Reports of permethrin resistance of Sarcoptes scabiei var. hominis are emerging. We propose that this may be pseudoresistance. The resistance is due to inadequate counselling by physicians, incorrect treatment (insufficient quantity of permethrin; too short length of treatment), and poor adherence and compliance by patients. Other reasons include single application of permethrin, suggestion to apply the drug for 6-8 hours, failed application on subungual folds, irritant contact dermatitis, in particular on genitals, for which some patients stop the treatment, and unexplainable use of permethrin in post-scabies prurigo. Thus, we believe that several cases of resistance to permethrin are actually cases of pseudoresistance.

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Published

2023-05-31

How to Cite

Veraldi S, Schianchi R, Silvio M, Aromolo IF (2023) Pseudoresistance to permethrin in scabies. J Infect Dev Ctries 17:713–715. doi: 10.3855/jidc.17750

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Issue

Vol. 17 No. 05: May 2023

Section

Letters to the Editor

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