The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient

Aynaz Ghojoghi; Sadegh Khodavaisy; Ali Zarei Mahmoudabadi; Maryam Hatami; Mahnaz Fatahinia

doi:10.3855/jidc.18099

The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient

Authors

Aynaz Ghojoghi Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran https://orcid.org/0000-0001-6055-2489
Sadegh Khodavaisy Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Ali Zarei Mahmoudabadi Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran https://orcid.org/0000-0002-5347-2082
Maryam Hatami Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
Mahnaz Fatahinia Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran https://orcid.org/0000-0001-6898-1309

DOI:

https://doi.org/10.3855/jidc.18099

Keywords:

Geotrichum, Magnusiomyces capitatus, diagnosis, addiction, nystatin

Abstract

Magnusiomyces capitatus (M. capitatus) is an emerging opportunistic yeast, rarely found as a causal agent of invasive fungal infection. In this study, we report a 31-year-old man infected with M. capitatus in the oral cavity, with a history of heroin and amphetamine abuse. M. capitatus was isolated through culture and microscopic analysis and identified by PCR amplification of the ITS DNA region. Based on the in vitro antifungal susceptibility test, the lowest MICs for M. capitatus were recorded for nystatin, itraconazole, and amphotericin, while higher MICs were observed for caspofungin and fluconazole. Treatment with nystatin successfully eliminated M. capitatus and relieved the clinical symptoms. This study presents the first case of M. capitatus in a patient with substance use disorder, manifesting as a plaque-like ulcer in the oral cavity.

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Published

2024-02-29

How to Cite

Ghojoghi A, Khodavaisy S, Zarei Mahmoudabadi A, Hatami M, Fatahinia M (2024) The first case of isolation of Magnusiomyces capitatus from the oral cavity of an addicted patient. J Infect Dev Ctries 18:309–314. doi: 10.3855/jidc.18099

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Issue

Vol. 18 No. 02: February 2024

Section

Case Reports

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